CRLF2 and eosinophilic esophagitis: Over time, studies of other candidate genes showed an association of EoE susceptibility also with the TSLP receptor: CRFL2 (cytokine receptor-like factor 2), FLG (filaggrin), and CCL26 (eotaxin 3) which was overexpressed about 50-fold compared with controls which have considerably strengthened its role in EoE pathogenesis [38,46].