This set of target genes was also confirmed in leukemias induced in mice transformed by MLL-AF9 (HoxA9, HoxA10, Evi1 (MECOM), HoxA2, HoxA7 HoxA3, and HoxA13) and also induced iMLL-AF9 in mice HoxA9, HoxA10, Meis1, Eya1, Mef2c, Myb, and Six1 [7,19]. Here, KMT2A is linked to leukemia.