This set of target genes was also confirmed in leukemias induced in mice transformed by MLL-AF9 (HoxA9, HoxA10, Evi1 (MECOM), HoxA2, HoxA7 HoxA3, and HoxA13) and also induced iMLL-AF9 in mice HoxA9, HoxA10, Meis1, Eya1, Mef2c, Myb, and Six1 [7,19]. The gene discussed is MLLT3; the disease is leukemia.