ZNF521 and acute myeloid leukemia: When considering the FAB subgroups, the highest levels of ZNF521 mRNA expression were observed in M0, while the lowest amounts were expressed in M3 AMLs (p = 6.02 × 10−3), indicating that elevated ZNF521 expression correlates with minimally differentiated acute myeloblastic leukemia (M0-AML), a rare type of AML that is associated with poor prognosis (GSE6891) (Figure 1C).