At this time, cancer researcher Axel Ullrich and medical oncologist Denis Slamon highlighted the substantial information accumulating in relation to the role of the HER2/neu oncogene in 20–25% of breast tumours and recognised targeting this receptor on the cell surface by a monoclonal antibody, trastuzumab, which could inhibit cell signaling, impair oncogenesis, and improve clinical outcomes for patients [34,35,36]. The gene discussed is ERBB2; the disease is cancer.