Treatment of ST3-induced rats with mono- or combination therapy (MET and/or CTS-SeNP) resulted in normal levels of diabetes biomarker activity: AST (aspartate transaminase), ALT (alanine transaminase), GGT (gamma glutamyl transpeptidase), and ALP (alkaline phosphatase), which are closely associated with liver tissue damage [186]. Here, GPT is linked to diabetes mellitus.