NFKB1 and COVID-19: Regarding the underlying signaling pathways, recent data suggest that the NF-κB pathway is one of the central signaling pathways for the SARS-CoV-2 infection-induced proinflammatory cytokine/chemokine response, playing a central role in the severity and lethality of COVID-19 [32,33,34,35,36,37,38].