Consistent with these results, the expression of inflammatory cytokines, such as TNF-α, IL-6, IL-17, and IL-36γ, in IMQ-induced psoriasis-like skin lesions was significantly higher than that in the control; however, ki16425 treatment significantly reduced the expression of these genes when compared with that in IMQ-Veh group (Figure 1D). This evidence concerns the gene IL17A and psoriasis.