MYOF and neoplasm: In addition, the metabolic adaptations of tumors to specific conditions, such as methionine sensitivity (related to tumor cells proliferation) [38], the expression of the Mucin1 glycoprotein (modulatory role in cancer metabolism) [39], the depletion of membrane protein myoferlin (and subsequent impact on metastasis extension) [63], hypoxia [40,62], the extent of glucose metabolism (associated with tumor malignancy) [41] and breast cancer gene 1 (BRCA1) mutations [42], have been investigated.