CD8A and neoplasm: One of the main final outcomes of the described induction of interferon release is the activation of a subset of Th1 response associated CD11c+, CD8α+ BATF+ dendritic cells (DCs) [64] that migrate to lymph nodes, where they provoke cross-priming of effector CD8+ T cells that will access either the principal lesion or the non-irradiated distant sites, contributing to tumor eradication [65].