The luciferase signal was recovered without an inhibitor in MOLM-13luc+ following a heat-shock, but incubation of AML cells with MBZ or specific HSP inhibitors significantly impaired recovery of the signal (Figure 3E,F), suggesting a direct inhibition of HSP70/HSP90-mediated luciferase refolding. Here, HSPA1A is linked to acute myeloid leukemia.