However, much like was observed for the Wnt/β-catenin signaling pathway, neither Lox, Col1a1, Tgfβ, nor NF-κB mRNA levels were significantly impacted by Selenof-genotype in tumor tissues of AOM/DSS-treated WT and Selenof-KO mice. The gene discussed is TGFB1; the disease is infectious otitis media.