The upregulation of ADAR1 in the prostate, liver, chronic myelogenous leukaemia (CML), colorectal and cervical cancers has been found to target cancer-related mRNAs such as DHFR, BLCAP, and RRUNE1 [131]. The gene discussed is DHFR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.