Local expression of ghrelin has been observed in range of neoplasms, including, among others, oral, esophageal, gastric, pancreatic, colorectal, breast, ovarian, prostate, thyroid, lung, endometrial, and renal cancer; adrenocortical tumors; pituitary adenomas; and endocrine pancreatic tumors [234,235]. The gene discussed is GHRL; the disease is adrenal cortex neoplasm.