We found GAS itself was able to attract neutrophil migration regardless of whether the neutrophils were from WT, IL-33-KO, or ST2-KO mice, even though there are differences in migration efficiency among the three groups, indicating that there were other chemoattractants, distinct from the IL-33/ST2 axis, which could attract ST2-deficient neutrophil migration during infection (Figure 4). The gene discussed is IL33; the disease is infection.