NQO1 and intracerebral hemorrhage: Furthermore, Zhao and colleagues [56] demonstrated a 1.3-fold increase in Nqo1 expression in the striatum within 3 h after intracerebral hemorrhage injury and SFN injection, whereas Hong and colleagues [27] showed a one-fold increase of the same gene in the cortex after CCI and an additional 0.2-fold increase within 24 h after SFN treatment.