In VAT, the expression of hypoxia-inducible factor 1-alpha (HIF1A), ANGPT2 and the thermoregulatory gene cell death-inducing DFFA-like effector A (CIDEA) was found slightly decreased in NAFLD obese females (Table 3, Supplementary Figure S3). Here, ANGPT2 is linked to metabolic dysfunction-associated steatotic liver disease.