Finally, the ratio between LEP and ADIPOQ expression was increased in VAT of Ob-NAFLD patients (0.20 (0.10–0.41)) with respect to OB (0.10 (0.06–0.17), p = 0.046) while comparable in SAT from both groups (0.25 (0.14–0.33) vs. 0.27 (0.12–0.35), p = 0.696). The gene discussed is LEP; the disease is metabolic dysfunction-associated steatotic liver disease.