XRCC5 and autosomal dominant polycystic kidney disease: XRCC5 and XRCC6 were also increased by 1.79-fold (95% CI (1.68, 1.90); q < 0.01) and 1.65-fold (95% CI (1.53, 1.78); q < 0.001), respectively, in ADPKD tissue, and this was maintained in all cyst sizes (Table 1).