IL7 and colorectal cancer: Some of the signaling pathways correlated well with the biological processes identified in GSEA analysis, such as the colorectal cancer mestasis signaling vs. EMT, IL-7 signaling vs. interferon α/γ responses, osteroarthritis pathway vs. inflammatory response, etc. Therefore, inhibiting these pathways might be necessary to achieve naïve property from the primed-like biPSCs.