OXT and Impotence: In fact, since the first pioneering studies conducted in the 1960s that showed a facilitatory effect of oxytocin on male sexual behavior by revealing that intravenous-systemic oxytocin was either capable of decreasing the latency to the first ejaculation and of retarding the sexual exhaustion of male rabbits paired with a receptive female [53] as well as of ameliorating psychogenic impotence in a limited number of human patients [54], numerous other studies have confirmed that oxytocin is deeply involved in erectile function and copulatory behavior.