The recognition of the association between meningioma formation and neurofibromatosis 2 (NF-2) gene inactivation [11,12,13,14,15] over three decades ago has opened the door to the identification of countless genetic alterations of a growing number of non-NF-2 genes [16,17,18,19,20,21,22,23,24]. Here, NF2 is linked to meningioma.