In a European study done by Haferlach et al., 14 genes (ASXL1, CBL, ETV6, EZH2, KRAS, LAMB4, NF1, NPM1, NRAS, PRPF8, RUNX1, STAG2, TET2 and TP53) were shortlisted to stratify MDS patients into four risk groups (low, intermediate, high, and very high risk) in combination with conventional scoring or as standalone scoring tools [13]. The gene discussed is TP53; the disease is myelodysplastic syndrome.