This effect was mediated by the inactivation of cSRC and a subsequent reduction in hexokinase-2 (HK-2), glucose-6-phosphate dehydrogenase (G6PD), and glucose transporter-3 (GLUT-3) proteins, all of which are involved in the proliferation of glioblastoma stem cells through the uptake and usage of glucose [128]. The gene discussed is HK2; the disease is glioblastoma.