3.3. Adipocyte-Specific CXCR2 cKO Mice Have Lower Floating Tumor Burdens and Tumor-Attached Monocytes/Macrophages but Increased Vacuole Clumps in OC-Induced Ascites after Diet-Induced Obesity. The gene discussed is CXCR2; the disease is obesity due to melanocortin 4 receptor deficiency.