CXCR2 and obesity due to melanocortin 4 receptor deficiency: Crown-like structures in the adipose tissues were not different between CXCR2 WT and cKO mice but there was an approximate 2-fold increase in both HFD-fed mice (Figure 1D), indicating the stimulation of the proinflammatory processes in the adipose tissue due to obesity in HFD-fed mice.