MET and non-small cell lung carcinoma: In another study that investigated a large cohort of patients with surgically resected NSCLC for MET overexpression and gene amplification, Sterlacci et al. found MET amplification in 2.4% of cases assessed by FISH using tissue microarrays (using a defined cut-off for amplifications of MET to CEN7 signal ratio of ≥2.0) [38].