G1 PanNETs were the most represented group within the EZH2low category (n = 55/80, 69%), whereas G2 PanNETs were prevalent when EZH2 expression was intermediate (n = 32/56, 57%) or high (n = 21/36, 58%), as depicted in Figure 1B. A significant association between EZH2 expression and tumor grade was confirmed after exclusion of patients with functioning neoplasms (p < 0.001). The gene discussed is EZH2; the disease is neoplasm.