First, we selected the down-regulated genes at PNX0010 under PARG overexpression (Figure 5A) that are related to cancer development: ID1, ID2, ID3, and SERPINE1 and performed qPCR analysis for 786-O, 769-P, SK-RC-45, and SK-RC-26b cell lines treated with the 10 uM PARP-1 inhibitor rucaparib for 24 h (Figure S4). The gene discussed is PARG; the disease is cancer.