Therefore, this study aims to investigate the effect of endocrine-disrupting treatments (aromatase and STS inhibitors) on estrogen synthesis in cell cultures and xenografts from IBC and IMC cell lines (SUM149 and IPC-366), in order to determine cell viability, tumor progression, and the hormonal changes produced by the treatments and thus elucidate the efficacy of these treatments in IBC and IMC. Here, CYP19A1 is linked to neoplasm.