Aberrant expression of SDCBP in some cancers has been associated with tumor progression, metastatic dissemination, and poor prognosis via FAK, Src, p38-MAPK, AKT, NFκB, IGFBP2, EGFR, and VEGFR [9,27,28,29,30]. This evidence concerns the gene IGFBP2 and neoplasm.