RAC1 and cancer: We next used the KTC1 and PDX.008.CL cell lines, as well as the metastatic patient sample to quantify copy number and expression of several cancer-related genes located on chromosome 7p and 7q, including RAC1 (7p22.1) TWIST1 (7p21.1), EGFR1 (7p11.2), MET (7q31.2) and BRAF (7q.34).