An analysis of NNMT expression in melanoma samples from the Pan-Cancer Analysis of Whole Genomes (PCAWG) (https://www.ebi.ac.uk/gxa/home) (accessed on 14 September 2021) confirmed these findings, showing that the enzyme displayed an expression level of 26 transcript per million (TPM), while in other types of cancers, characterized by a marked overexpression of NNMT, such as bladder, lung, and breast cancer, an expression level of 21, 161, and 71 TPM, respectively, was detected. This evidence concerns the gene NNMT and cancer.