In the s-CLL cells, CD5 MFI positively correlated with CXCR3 percentage (r = 0.51, p < 0.05); in the l-CLL cells, CD5 MFI positively correlated with both CXCR3 percentage (r = 0.51, p < 0.05) and ZAP-70 MFI (r = 0.46, p < 0.05). This evidence concerns the gene CD5 and B-cell chronic lymphocytic leukemia.