In the GBM-sp (Figure 3a), the GSC markers STAT3, SOX2, PROM1, POU5F1, PDGFRA, NOTCH2, MYC, MSI1, L1CAM, ITGA6, CXCR4, and CD44 were significantly expressed in all cell lines (Figure 3b). The gene discussed is L1CAM; the disease is glioblastoma.