CD274 and neoplasm: In a pancreatic murine model (KPC), simultaneous (days 0, 3, 6, and 9) addition of anti-PD-L1 antibody to one fraction of 12 Gy was found to be more efficient on tumor growth than the sequential schedule (anti-PD-L1 at days 6, 9, 12, and 15) [43].