CD8A and neoplasm: Indeed, while 18 × 2 Gy induced a myeloid response with an increase in myeloid-derived suppressor cells (MDSC) and tumor-associated macrophages 2 (TAM2), 3 × 8 Gy and 1 × 16.4 Gy induced a lymphoid response with an increase in CD8+ T-cells and regulatory T-cells (Treg) [11].