The breast cancer cell lines were treated with a single drug or a drug combination for 48 h at 100-μM dose and cell lysate was used for the immunoblotting of various anti-apoptotic BCL-2 family isoforms [29] and proapoptotic caspase 3 and cleaved caspase 3 (CC3) [30] levels. Here, BCL2 is linked to breast carcinoma.