COL11A1 and ovarian carcinoma: In contrast, COL11A1 knockdown (measured by Western blot and RT-PCR (Figure 1E and Figure S1I)) in A2780CIS cells (a cisplatin-resistant ovarian cancer cell line that expresses high levels of endogenous COL11A1 [9]) led to decreased phosphorylated and total HSP27 protein expression (Figure 1E) as well as HSPB1 (a gene encoding HSP27) expression (Figure 1F) compared to the scrambled control cells (as expected).