A few examples of recently identified and thoroughly validated p53-repressed targets include genes encoding fibrillarin [52]; cancer-associated lipogenic enzyme SCD [53]; nestin, connecting p53 with cellular plasticity [46]; PINK1, which links nuclear p53 to the modulation of mitophagy [54]; c-Myc [55]; and IKKβ [56]. Here, TP53 is linked to cancer.