SNAI2 and melanoma: Instead, the authors points at direct interactions with a specific RNA-binding protein (RBP) insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), and CDR1as depletion in melanoma triggers IGF2BP3-mediated upregulation of SNAI2 and MEF2C that positively regulate invasion and transcription of neural crest genes, respectively [44].