Nuclear enriched abundant transcript 1 (NEAT1) is positively regulated by epidermal growth factor receptor (EGFR) pathway in glioblastoma and its expression contributes to cancer progression mostly via EZH2-dependent repression of several tumor suppressor genes, such as Axin2, inhibitor of beta-catenin and Tcf-4 (ICAT) and glycogen synthase kinase 3 beta (GSK3B) [179]. This evidence concerns the gene GSK3B and cancer.