TRIB2 and neoplasm: In addition to miR-153-3p sponging and controlling EMT, circRNA_0084043 has been also found to sponge another tumor suppressor miR-429, which negatively regulates Wnt/β-catenin pathway through binding to tribbles pseudokinase 2 (TRIB2) [118], a downstream effector gene of TCF transcription factors signaling [189].