Benign cells distant to tumor foci and tumor cells were isolated from the same FFPE tissue sections of five patients with Gleason grade 3 + 3 or 3 + 4, and the analysis was performed on pooled samples (of two ERG+ tumors, of three ERG− tumors, and of five benign specimens): 1196 DEPs were identified, of which 518 and 500 were unique to ERG+ and ERG− tumor cells, respectively. This evidence concerns the gene ERG and neoplasm.