More recently, several genome-wide sequencing studies performed on clinical samples of prostate tumors revealed multiple recurrent alterations that involve both coding and non-coding genes that were not previously implicated in prostate cancer tumorigenesis, such as those of NCOA2, FOXA1, SPOP, and IDH1 [23,24,25,26]. The gene discussed is FOXA1; the disease is Familial prostate cancer.