Notably, alterations in homologous recombination deficiency (HRD)-related genes, such as BRCA1, BRCA2, ATM, and KMT2A, were detected in both SeC-Os and SeC-EOs, suggesting a possible role of poly (ADP-ribose) polymerase inhibitors [57,58]. The gene discussed is BRCA1; the disease is hypoparathyroidism-retardation-dysmorphism syndrome.