BCAT1 and cancer: BCAT1 has been reported to be overexpressed in a number of forms of cancer; however, its role remains unclear as it appears to promote tumorigenesis and is required to maintain cell growth in some forms of cancer including gastric, endometrial and gliomas whereas in pancreatic and ovarian tumors, this gene is overexpressed but is not essential for viability [115,116,117,118,119,120].