EGFR and cancer: Conversely, in the exosomes of IH-exposed CRL-1675 cells, the miRNAs that were differentially expressed were likely to target pathways such as transcriptional mis-regulation in cancer (hsa05202, p = 2.37 × 10−4), the ErbB signaling pathway (hsa04012, p = 4.87 × 10−4) and the Sphingolipid signaling pathway (hsa04071, p = 9.34 × 10−4) (Table 2).