In addition to ALK and ASCL1 that were previously reported in the context of neuroblastoma, a novel interesting candidate gene “Claspin” (Clspn) was identified, for which recently a critical role was described in protection of cancer cells from replication stress and which has been reported as a key gene in normal developmental controlled gene amplification in Drosophila [67]. Here, CLSPN is linked to neuroblastoma.