MYCN and neuroblastoma: To further delineate putative relevant novel codrivers in MYCN overexpressing neuroblastomas, we performed cross-section of dynamically upregulated genes in TH-MYCN mice from Weeks 1 to 2 with the “CRISPR Avana screen” identified dependencies from the DEPMAP initiative common between included MYCN-amplified and neuroblastoma cell lines [28,61].