To determine if PP2A is involved in ESCC progression, we analyzed Kaplan-Meier Plotter datasets (http://kmplot.com, accessed date: 8 November 2019) and found that the expression level of PPP2CA, the major catalytic subunit of PP2A, was negatively correlated with the overall survival rate of esophageal cancer (Supplementary Figure S1A,B). The gene discussed is PPP2CA; the disease is esophageal squamous cell carcinoma.