In patients with breast cancer, the administration of paclitaxel or docetaxel increases the serum levels of IL-2, IL-6, IFN-γ, and granulocyte macrophage colony-stimulating factor (GM-CSF) and peripheral NK cell activity, whereas NAC decreases the levels of IL-1 and TNF-α [32]. This evidence concerns the gene CSF2 and breast carcinoma.