TMEM expression was also dependent on tumor invasion to space surrounding a nerve for ANO1, TMEM116, and TMEM97 (p = 0.002, p < 0.0001, p = 0.008) and on angiolymphatic invasion for TMEM48, RTP3, TMEM173, and TMEM116 (p < 0.0001, p = 0.0267, p = 0.001, p = 0.0053, respectively). This evidence concerns the gene TMEM116 and neoplasm.