CXCL6 and non-small cell lung carcinoma: Our findings therefore provide insight into the underlying mechanisms of recruitment-related chemokines in TANs infiltration, and found that the production of CXCL6 increased in NSCLC cells under hypoxic condition, and the blockade of CXCL6 almost halted TANs migration, suggesting that the recruitment of TANs is mediated mainly by CXCL6.