AKT1 and neoplasm: Pathways involved in epithelial-mesenchymal transition (EMT), IL-6/JAK2/STAT3, PI3K/Akt/MTOR, Hypoxia, MYC targets V1 and Angiogenesis were activated in Cluster 2 (worse survival), whereas Cluster 1 (favorable survival), revealed enrichment of pathways correlated to tumor progression, including EMT, hypoxia, and angiogenesis (Figure.