In summary, POU2AF1 was significantly up-regulated in large AAA samples both in GSE98278 (8.077 ± 1.976 vs 6.386 ± 1.580, p < 0.05) and GSE57691 (8.787 ± 1.085 vs 7.848 ± 1.047, p < 0.01) (Figure 4e). This evidence concerns the gene POU2AF1 and triple-A syndrome.