ACE2 and COVID-19: In order to be able to comprehend the potential association of ACE2 rs2106809 T-allele with COVID-19 epidemiology, the distribution of population bearing the T-allele (TT/T genotype) was analysed along with COVID-19 morbidity (cases per million population) and mortality (case fatality rate per million COVID-19 cases), as shown in figure 1 (see also electronic supplementary material).