CAP1 and cancer: It was observed that CAP1-high-expression mRNA level associated with poor prognosis in various cancers, which include cervical squamous cell carcinoma, head–neck squamous cell carcinoma, kidney renal papillary cell carcinoma, liver hepatocellular carcinoma, lung squamous cell carcinoma, and pancreatic ductal adenocarcinoma (Fig. 1b–g).