To address thisquestion, we used qRT-PCR to measure the abundance of the IFNA1, IFNB1,JUN and HSPB3 mRNAs in nuclear and cytoplasmic fractions of tumor celllysates of three lung adenocarcinomas expressing high and three expressing lowlevels of IWS1/p-IWS1 (Fig. 3c Upperpanel). The gene discussed is IFNA1; the disease is lung adenocarcinoma.