ITGAM and nutritional deficiency disease: In our study a significantly higher risk of cachexia was reported in elderly patients (≥ 74: OR 3.55), people with renal failure (OR 3.75), with a higher degree of CHF according to NYHA (III-IV: OR 2.83), with moderate or severe malnutrition according to SGA (B or C: OR 19.01) and AA genotype of ITGAM gene (OR 2.03).