PTPRC and congestive heart failure: In another study in the blood of 30 patients with CHF (NYHA II-IV), an increase in CD11b integrin was observed on the surface of CD45 + leukocytes (p = 0.03) and in the subpopulation of macrophages, monocytes (p = 0.001) and polymorphonuclear cells (p = 0.002).